Don't Let Depression Keep You Down​

Achieve TMS East now offers the only FDA-Approved Ketamine-Based psychedelic treatment for depression.

How To Get Started

1. No Cost Screening

Learn about esketamine nasal spray

The first person you’ll speak with will answer any questions you have about the treatment and how it works. They will then ask you some questions to review your mental health history to get an idea if we think you would qualify for Esketamine Nasal treatment.

We focus on insurance so you don’t have to

In this first conversation we will also explain treatment payment options, including going over standard insurance plan criteria with you. We will coordinate with your health insurance provider to determine benefits.


IV ketamine
  • Is not FDA-approved for the treatment of depression
  • Is not covered by many insurance companies
  • Is not offered at Achieve TMS East
Esketamine nasal spray (Spravato®)
  • Is FDA-approved for the treatment of depression
  • Is covered by many insurance companies
  • Is offered at Achieve TMS East


No! Many major insurance companies cover ketamine-based depression treatment if you haven’t gotten better after trying just TWO antidepressants.

2. Pre-Treatment Assessment

Figure out if psychedelic ketamine-based depression treatment is right for you

The first appointment you will have is a free Informational Session. Here you will get to see the office, meet the staff, and fill out the necessary paperwork to get started. After our team has collected all the records we need, we will determine if we can get insurance coverage for the patient and schedule the next step.

The next step is a psychiatric evaluation with one of our doctors or psychiatric nurse practitioners. In this evaluation our provider will determine if they think Esketamine Nasal Spray treatment is a good option for you. 

3. Treatment

You’re ready to start feeling better!

Before treatment, don’t eat anything for two hours and don’t have any large amounts of fluids for 30 minutes.

At most Achieve TMS East centers, we try to book esketamine nasal spray treatments in the afternoon to accommodate your schedule. You’d come into the Achieve TMS East center during the afternoon and get treated, go home, have dinner, then go to bed. By the next morning, most people are ready to resume their day with no restrictions.


  1. Arrive at the center and relax in a chair.

  2. The spray is handed to you directly, and you self-administer it.

  3. Wait 2 hours in the center.

  4. Have someone drive you home. 

Your safety & comfort are our top priorities

Because esketamine is a psychedelic treatment for depression, during treatment you may feel dizzy, euphoric, or intoxicated. Throughout your treatment, our Care Team will be on-site to assist you. Your blood pressure will be checked at baseline, 40 minutes in, and before you leave.

After treatment, you’ll be groggy and woozy. You can’t do anything hazardous for the rest of your day. That includes operating a motor vehicle, so you’ll need someone to drive you home after treatment.

Typical Treatment Course

2 treatments a week for 4 weeks

1 treatment a week for 4 weeks

1 treatment every 1-2 weeks

Where to find nasal esketamine spray for depression

Achieve TMS East Centers are private, relaxing, & REMS-Certified

Curious about ketamine-based therapy for depression?

Our representatives will help you find out if esketamine nasal spray is right for you!

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Esketamine Nasal Spray FAQs

Spravato® is nasal esketamine, a more specific form of ketamine designed to treat depression.

Spravato® takes the effective part of ketamine and isolates that and then gets rid of the sedating part of ketamine that is not believed to be as important for depression.

Yes. You have to be on an antidepressant medication to receive nasal esketamine spray.

Esketamine nasal spray is FDA-approved for people with depression who have not experienced adequate improvement with antidepressant medications.

No. Nasal esketamine must be given at a REMS (risk evaluation and mitigation system) certified center, such as an Achieve TMS East center.

A typical round of esketamine nasal spray treatment consists of 12 sessions in three phases:

  • Phase 1: 2 treatments a weeks for 4 weeks
  • Phase 2: 1 treatment a week for 4 weeks
  • Phase 3: 1 treatment every 1-2 weeks

Before coming to each appointment, be sure you avoid eating anything for two hours. You should also avoid large amounts of fluid for 30 minutes before an appointment.

Each session takes place at a private, Achieve TMS East center. Once you arrive, you'll sit in a chair and self-administer the nasal spray. Your blood pressure is checked at the start of the session, 40 mins into treatment, and prior to leaving the center. 

You have to stay in the center for no less than two hours. Make sure you have someone to drive you home. 

No. Esketamine nasal spray is FDA-approved for people with depression who have not experienced adequate improvement with antidepressant medications.

You'll spray either  2 or 3 sprays in your nostril depending on the dose. 

You shouldn't take esketamine nasal spray if you have:

  • Uncontrolled hypertension
  • History of strokes or brain bleeds
  • Abnormal blood vessels at risk of bleeding, such as aneurysms or ateriorvenous malformations (AVMs)
  • Sensitivity to eketamine

View Indications and Important Safety Information.

That's okay! Our clinical team will help you decide if ketamine-based depression treatment is right for you. If it isn't, Achieve TMS East also offers TMS therapy, which is a non-drug, non-sedating FDA-cleared treatment for depression. You can learn more about TMS by asking our representatives. Reach out to us here.

Yes! It's covered by many major insurance companies. Achieve TMS East's insurance team will handle all the insurance for you. On average, an insurance company will cover about 28 treatment sessions.

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